2-Metilisocitratna dehidrataza
| 2-metilisocitratna dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.99 | ||||||||
| CAS broj | 170780-51-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
2-metilisocitratna dehidrataza (EC 4.2.1.99, (2S,3R)-3-hidroksibutan-1,2,3-trikarboksilatna hidrolijaza) je enzim sa sistematskim imenom (2S,3R)-3-hidroksibutan-1,2,3-trikarboksilat hidrolijaza (formira (Z)-but-2-en-1,2,3-trikarboksilat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (2S,3R)-3-hidroksibutan-1,2,3-trikarboksilat (Z)-but-2-en-1,2,3-trikarboksilat + H2O
Enzim iz gljive Yarrowia lipolitica (Saccharomycopsis) ne deluje na izocitrat.
- ↑ Aoki, H., Uchiyama, H., Umetsu, H., Tabuchi, T. (1995). „Isolation of 2-methylisocitrate dehydratase, a new enzyme serving in the methylcitric acid cycle for propionate metabolism, from Yarrowia lipolytica”. Biosci. Biotechnol. Biochem. 59: 1825-1828.
- ↑ Tabuchi, T., Umetsu, H., Aoki, H., Uchiyama, H. (1995). „Characteristics of 2-methylisocitrate dehydratase, isolated from Yarrowia lipolytica, in comparison to aconitase”. Biosci. Biotechnol. Biochem. 59: 2013-2017.
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