X-Trp aminopeptidaza
(Preusmjereno sa stranice X-Trp aminopeptidase)
| X-Trp aminopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.11.16 | ||||||||
| CAS broj | 137010-33-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
X-Trp aminopeptidaza (EC 3.4.11.16, aminopeptidaza W, aminopeptidaza X-Trp) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvajanje N-terminalnih ostataka (posebno glutamata i leucina) sa peptida, pod uslovom da je triptofan (ili bar fenilalanin ili tirozin) pretposlednji ostatak. Takođe deluje na Glu-Trp, Leu-Trp i brojne druge dipeptide
Ovaj glikoprotein sadrži Zn2+.
Reference[uredi | uredi kod]
- ↑ Gee, N.S. and Kenny, A.J. (1985). „Proteins of the kidney microvillar membrane. The 130kDa protein in pig kidney, recognised by monoclonal antibody GK5C1, is an ectoenzyme with aminopeptidase activity”. Biochem. J. 230: 753-764. PMID 4062876.
- ↑ Gee, N.S. and Kenny, A.J. (1987). „Proteins of the kidney microvillar membrane. Enzymic and molecular properties of aminopeptidase W”. Biochem. J. 246: 97-102. PMID 2890346.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.