Valin dehidrogenaza (NADP+)
| Valin dehidrogenaza (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.1.8 | ||||||||
| CAS broj | 37255-39-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Valin dehidrogenaza (NADP+) (EC 1.4.1.8, valinska dehidrogenaza (nikotinanid adenin dinukleotid fosfat), valinska dehidrogenaza (NADP)) je enzim sa sistematskim imenom L-valin:NADP+ oksidoreduktaza (deaminacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-valin +H2O + NADP+ 3-metil-2-oksobutanoat + NH3 + NADPH + H+
- ↑ Kagan, Z.S., Kretovich, V.L. and Polyakov, V.A. (1966). „Biosynthesis of valine by reductive amination of its keto analogue in plants”. Enzymologia 30: 343-366. PMID 6005410.
- ↑ Kagan, Z.S., Polyakov, V.A. and Kretovich, V.L. (1968). „Soluble valine dehydrogenase from roots of plant seedings”. Biochemistry (Mosc) 33: 74-84. PMID 4385962.
- ↑ Kagan, Z.S., Polyakov, V.A. and Kretovich, V.L. (1969). „Purification and properties of valine dehydrogenase”. Biochemistry (Mosc) 34: 47-51. PMID 4389825.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.