Ubihinol oksidaza (H+-transport)
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| Ubihinol oksidaza (H+-transport) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.10.3.10 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ubihinol oksidaza (H+-transport) (EC 1.10.3.10, citohrom bb3 oksidaza, citohrom bo oksidaza, citohrom bd-I oksidaza) je enzim sa sistematskim imenom ubihinol:O2 oksidoreduktaza (H+-transporting).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim sadrži dinuklearni centar koji se sastoji od dva hema, ili hema i bakra.
Reference[uredi | uredi kod]
- ↑ Abramson, J., Riistama, S., Larsson, G., Jasaitis, A., Svensson-Ek, M., Laakkonen, L., Puustinen, A., Iwata, S. and Wikstrom, M. (2000). „The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding site”. Nat. Struct. Biol. 7: 910-917. PMID 11017202.
- ↑ Belevich, I., Borisov, V.B., Zhang, J., Yang, K., Konstantinov, A.A., Gennis, R.B. and Verkhovsky, M.I. (2005). „Time-resolved electrometric and optical studies on cytochrome bd suggest a mechanism of electron-proton coupling in the di-heme active site”. Proc. Natl. Acad. Sci. USA 102: 3657-3662. PMID 15728392.
- ↑ Yap, L.L., Lin, M.T., Ouyang, H., Samoilova, R.I., Dikanov, S.A. and Gennis, R.B. (2010). „The quinone-binding sites of the cytochrome bo3 ubiquinol oxidase from Escherichia coli”. Biochim. Biophys. Acta 1797: 1924-1932. PMID 20416270.
- ↑ Shepherd, M., Sanguinetti, G., Cook, G.M. and Poole, R.K. (2010). „Compensations for diminished terminal oxidase activity in Escherichia coli: cytochrome bd-II-mediated respiration and glutamate metabolism”. J. Biol. Chem. 285: 18464-18472. PMID 20392690.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.