Flavonol-3-O-glukozid L-ramnoziltransferaza
(Preusmjereno sa stranice UDP-L-ramnoza:flavonol-3-O-D-glukozid 6''-O-L-ramnoziltransferaza)
| Flavonol-3-O-glukozid L-ramnoziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.159 | ||||||||
| CAS broj | 83380-89-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Flavonol-3-O-glukozid L-ramnoziltransferaza (EC 2.4.1.159, uridin difosforamnoza-flavonol 3-O-glukozid ramnoziltransferaza, UDP-ramnoza:flavonol 3-O-glukozid ramnoziltransferaza) je enzim sa sistematskim imenom UDP-L-ramnoza:flavonol-3-O-D-glukozid 6-O-L-ramnoziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-L-ramnoza + flavanol3-O-D-glukozid UDP + flavanol3-O-[beta-L-ramnozil-(1->6)-beta-D-glukozid]
Ovaj enzim konvertuje flavonol 3-O-glukozide u 3-O-rutinozide. On u manjoj meri deluje na rutin, kvercetin 3-O-galaktozid i flavonol 3-O-ramnozide.
Reference[uredi | uredi kod]
- ↑ Kleinehollenhorst, G., Behrens, H., Pegels, G., Srunk, N. and Wiermann, R. (1982). „Formation of flavonol 3-O-diglycosides and flavonol 3-O-triglycosides by enzyme extracts from anthers of Tulipa cv apeldoorn - characterization and activity of 3 different O-glycosyltransferases during anther development”. Z. Natursforsch. C: Biosci. 37: 587-599.
- ↑ Jones, P., Messner, B., Nakajima, J., Schaffner, A.R. and Saito, K. (2003). „UGT73C6 and UGT78D1, glycosyltransferases involved in flavonol glycoside biosynthesis in Arabidopsis thaliana”. J. Biol. Chem. 278: 43910-43918. PMID 12900416.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.