A-tubulin N-acetiltransferaza
(Preusmjereno sa stranice Tubulin N-acetyltransferase)
| A-tubulin N-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.108 | ||||||||
| CAS broj | 99889-90-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
A-tubulin N-acetiltransferaza (EC 2.3.1.108, alfa-tubulin acetilaza, TAT, alfa-tubulin acetiltransferaza, tubulin N-acetiltransferaza, acetil-KoA:alfa-tubulin-L-lizin N-acetiltransferaza, acetil-KoA:(alfa-tubulin)-L-lizin 6-N-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:(alfa-tubulin)-L-lizin N6-acetiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + [alfa-tubulin]-L-lizin KoA + [alfa-tubulin]-N6-acetil-L-lizin
Enzim iz Chlamydomonas flagella takođe acetiluje moždani alfa-tubulin sisara.
Reference[uredi | uredi kod]
- ↑ Greer, K., Maruta, H., L'Hernault, S.W. and Rosenbaum, J.L. (1985). „α-Tubulin acetylase activity in isolated Chlamydomonas flagella”. J. Cell Biol. 101: 2081-2084. PMID 4066751.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.