Tiocijanatna hidrolaza
(Preusmjereno sa stranice Tiocijanat hidrolaza)
| Tiocijanatna hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.5.8 | ||||||||
| CAS broj | 142539-65-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Tiocijanatna hidrolaza (EC 3.5.5.8) je enzim sa sistematskim imenom tiocijanat aminohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- tiocijanat + 2H2O karbonil sulfid + NH3 + HO-
Enzim iz Tiobacillus tioparus katalizuje prvi korak degradacije tiocijanata.
Reference[uredi | uredi kod]
- ↑ Katayama, Y., Matsushita, Y., Kaneko, M., Kondo, M., Mizuno, T. and Nyunoya, H. (1998). „Cloning of genes coding for the three subunits of thiocyanate hydrolase of Thiobacillus thioparus THI 115 and their evolutionary relationships to nitrile hydratase”. J. Bacteriol. 180: 2583-2589. PMID 9573140.
- ↑ Katayama, Y., Narahara, Y., Inoue, Y., Amano, F., Kanagawa, T. and Kuraishi, H. (1992). „A thiocyanate hydrolase of Thiobacillus thioparus”. J. Biol. Chem. 267: 9170-9175. PMID 1577754.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.