Telurit metiltransferaza
Prijeđi na navigaciju
Prijeđi na pretragu
| Telurit metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.265 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Telurit metiltransferaza (EC 2.1.1.265, TehB) je enzim sa sistematskim imenom S-adenozil-L-metionin:telurit metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + telurit S-adenozil-L-homocistein + metanteluronat
Ovaj enzim učestvuje u detoksifikaci telurita. On takođe može da metiliše selenit i selenijum dioksid.
Reference[uredi | uredi kod]
- ↑ Liu, M., Turner, R.J., Winstone, T.L., Saetre, A., Dyllick-Brenzinger, M., Jickling, G., Tari, L.W., Weiner, J.H. and Taylor, D.E. (2000). „Escherichia coli TehB requires S-adenosylmethionine as a cofactor to mediate tellurite resistance”. J. Bacteriol. 182: 6509-6513. PMID 11053398.
- ↑ Choudhury, H.G., Cameron, A.D., Iwata, S. and Beis, K. (2011). „Structure and mechanism of the chalcogen-detoxifying protein TehB from Escherichia coli”. Biochem. J. 435: 85-91. PMID 21244361.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.