TRNKMet citidin acetiltransferaza
| TRNKMet citidin acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.193 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
TRNKMet citidin acetiltransferaza (EC 2.3.1.193, YpfI, TmcA) je enzim sa sistematskim imenom acetil-KoA:(elongator tRNKMet)-citidin34 N4-acetiltransferaza (ATP-hidrolizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- [elongator tRNKMet]-citidin34 + ATP + acetil-KoA KoA + [elongator tRNKMet]-N4-acetilcitidin34 + ADP + fosfat
Ovaj enzim acetiluje pokretnu base C34 u CAU antikodonu elongaciono-specifičnog tRNKMet.
- ↑ Ikeuchi, Y., Kitahara, K. and Suzuki, T. (2008). „The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon”. EMBO J. 27: 2194-2203. PMID 18668122.
- ↑ Chimnaronk, S., Suzuki, T., Manita, T., Ikeuchi, Y., Yao, M., Suzuki, T. and Tanaka, I. (2009). „RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon”. EMBO J. 28: 1362-1373. PMID 19322199.
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