TRNK (5-metilaminometil-2-tiouridilat)-metiltransferaza
(Preusmjereno sa stranice TRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase)
| tRNK (5-metilaminometil-2-tiouridilat)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.61 | ||||||||
| CAS broj | 39391-17-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
tRNK (5-metilaminometil-2-tiouridilat)-metiltransferaza (EC 2.1.1.61, transfer ribonukleat 5-metilaminometil-2-tiouridilatna 5-metiltransferaza, tRNK 5-metilaminometil-2-tiouridilatna 5'-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:tRNK (5-metilaminometil-2-tio-uridilat)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + tRNK sa 5-aminometil-2-tiouridinom S-adenozil-L-homocistein + tRNK sa 5-metilaminometil-2-tiouridilatom
Ovaj enzim je specifična za terminalnu metil grupu 5-metilaminometil-2-tiouridilata.
Reference[uredi | uredi kod]
- ↑ Taya, Y. and Nishimura, S. (1973). „Biosynthesis of 5-methylaminomethyl-2-thiouridylate. I. Isolation of a new tRNA-methylase specific for 5-methylaminomethyl-2-thiouridylate”. Biochem. Biophys. Res. Commun. 51: 1062-1068. PMID 4703553.
- ↑ Taya, Y. and Nishimura, S. (1977). Salvatore, F., Borek, E., Zappia, V., Williams-Ashman, H.G. and Schlenk, F.. ur. The Biochemistry of Adenosylmethionine. New York: Columbia University Press. str. 251-251.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Taya, Y. and Nishimura, S. (1977). Salvatore, F., Borek, E., Zappia, V., Williams-Ashman, H.G. and Schlenk, F.. ur. The Biochemistry of Adenosylmethionine. New York: Columbia University Press. str. 251-251.