TRNKMet citidin acetiltransferaza
(Preusmjereno sa stranice TRNAMet cytidine acetyltransferase)
| TRNKMet citidin acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.193 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
TRNKMet citidin acetiltransferaza (EC 2.3.1.193, YpfI, TmcA) je enzim sa sistematskim imenom acetil-KoA:(elongator tRNKMet)-citidin34 N4-acetiltransferaza (ATP-hidrolizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- [elongator tRNKMet]-citidin34 + ATP + acetil-KoA KoA + [elongator tRNKMet]-N4-acetilcitidin34 + ADP + fosfat
Ovaj enzim acetiluje pokretnu base C34 u CAU antikodonu elongaciono-specifičnog tRNKMet.
Reference[uredi | uredi kod]
- ↑ Ikeuchi, Y., Kitahara, K. and Suzuki, T. (2008). „The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon”. EMBO J. 27: 2194-2203. PMID 18668122.
- ↑ Chimnaronk, S., Suzuki, T., Manita, T., Ikeuchi, Y., Yao, M., Suzuki, T. and Tanaka, I. (2009). „RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon”. EMBO J. 28: 1362-1373. PMID 19322199.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.