Sve-trans-nonaprenil-difosfat sintaza (geranil-difosfat specifična)
Prijeđi na navigaciju
Prijeđi na pretragu
| Sve-trans-nonaprenil-difosfat sintaza (geranil-difosfat specifična) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.84 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Sve-trans-nonaprenil-difosfat sintaza (geranil-difosfat specifična) (EC 2.5.1.84, nonaprenil difosfatna sintaza, solanezil difosfatna sintaza, SolPP sintaza, SPP-sintaza, SPP sintaza, solanezil-difosfatna sintaza, OsSPS2) je enzim sa sistematskim imenom geranil-difosfat:izopentenil-difosfat transtransferaza (dodaje 7 izopentenilnih jedinica).[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- geranil difosfat + 7 izopentenil difosfat 7 difosfat + sve-trans-nonaprenil difosfat
(2E,6E)-farnezil difosfat i geranilgeranil difosfat su manje efektivni supstrati od geranil difosfata.
Reference[uredi | uredi kod]
- ↑ Sagami, H., Ogura, K. and Seto, S. (1977). „Solanesyl pyrophosphate synthetase from Micrococcus lysodeikticus”. Biochemistry 16: 4616-4622. PMID 911777.
- ↑ Fujii, H., Sagami, H., Koyama, T., Ogura, K., Seto, S., Baba, T. and Allen, C.M. (1980). „Variable product specificity of solanesyl pyrophosphate synthetase”. Biochem. Biophys. Res. Commun. 96: 1648-1653. PMID 7447947.
- ↑ Ohara, K., Sasaki, K. and Yazaki, K. (2010). „Two solanesyl diphosphate synthases with different subcellular localizations and their respective physiological roles in Oryza sativa”. J. Exp. Bot.: -. PMID 20421194.
- ↑ Ohnuma, S., Koyama, T. and Ogura, K. (1991). „Purification of solanesyl-diphosphate synthase from Micrococcus luteus. A new class of prenyltransferase”. J. Biol. Chem. 266: 23706-23713. PMID 1748647.
- ↑ Gotoh, T., Koyama, T. and Ogura, K. (1992). „Farnesyl diphosphate synthase and solanesyl diphosphate synthase reactions of diphosphate-modified allylic analogs: the significance of the diphosphate linkage involved in the allylic substrates for prenyltransferase”. J. Biochem. 112: 20-27. PMID 1429508.
- ↑ Teclebrhan, H., Olsson, J., Swiezewska, E. and Dallner, G. (1993). „Biosynthesis of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes”. J. Biol. Chem. 268: 23081-23086. PMID 8226825.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.