Retinolna izomeraza
(Preusmjereno sa stranice Retinol izomeraza)
| Retinolna izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.2.1.7 | ||||||||
| CAS broj | 109740-80-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Retinolna izomeraza (EC 5.2.1.7, sve-trans-retinolna izomeraza) je enzim sa sistematskim imenom sve-trans-retinol 11-cis-trans-izomeraza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- sve-trans-retinol 11-cis-retinol
Ovaj enzim konvertuje sve-trans-retinol u 11-cis-retinol u odsustvu svetla.
Reference[uredi | uredi kod]
- ↑ Bernstein, P.S., Law, W.C. and Rando, R.R. (1987). „Isomerization of all-trans-retinoids to 11-cis-retinoids in vitro”. Proc. Natl. Acad. Sci. USA 84: 1849-1853. PMID 3494246.
- ↑ Bridges, C.D. and Alvarez, R.A. (1987). „The visual cycle operates via an isomerase acting on all-trans retinol in the pigment epithelium”. Science 236: 1678-1680. PMID 3603006.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.