Oploforus-luciferin 2-monooksigenaza
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| Oploforus-luciferin 2-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.12.13 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Oploforus-luciferin 2-monooksigenaza (EC 1.13.12.13, Oplophorus luciferaza) je enzim sa sistematskim imenom Oplophorus-luciferin:kiseonik 2-oksidoreduktaza (dekarboksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Oplophorus luciferin + O2 oksidovani Oplophorus luciferin + CO2 + hnu
Luciferaza iz dubinske lignje Oplophorus gracilorostris je kompleks koji se sastoji od više proteina. Enzim ima široku specifičnost. Koelenterazin i bisdezoksikoelenterazin su dobri supstrati.
Reference[uredi | uredi kod]
- ↑ Shimomura, O., Masugi, T., Johnson, F.H. and Haneda, Y. (1978). „Properties and reaction mechanism of the bioluminescence system of the deep-sea shrimp Oplophorus gracilorostris”. Biochemistry 17: 994-998. PMID 629957.
- ↑ Inouye, S., Watanabe, K., Nakamura, H., Shimomura, O. (2000). „Secretional luciferase of the luminous shrimp Oplophorus gracilirostris: cDNA cloning of a novel imidazopyrazinone luciferase”. FEBS Lett. 481: 19-25. PMID 10984608.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.