O-fosfo-L-serin—tRNK ligaza
(Preusmjereno sa stranice O-phospho-L-serine:tRNACys ligase (AMP-forming))
| O-fosfo-L-serin—tRNK ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.1.1.27 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
O-fosfo-L-serin—tRNK ligaza (EC 6.1.1.27, O-fosfoseril-tRNK ligaza, nekanonička O-fosfoseril-tRNK sintetaza, SepRS) je enzim sa sistematskim imenom O-fosfo-L-serin:tRNKCis ligaza(formira AMP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
U organizmima poput Archaeoglobus fulgidus Cys-tRNKCys se formira indirektnim putem.
Reference[uredi | uredi kod]
- ↑ Fukunaga, R. and Yokoyama, S. (2007). „Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea”. Nat. Struct. Mol. Biol. 14: 272-279. PMID 17351629.
- ↑ Hauenstein, S.I. and Perona, J.J. (2008). „Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei”. J. Biol. Chem. 283: 22007-22017. PMID 18559341.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.