Kukurbitacin D23-reduktaza
(Preusmjereno sa stranice NAD(P)H: kukurbitacin B Delta23-oksidoreduktaza)
| Kukurbitacin D23-reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.5 | ||||||||
| CAS broj | 37256-38-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Kukurbitacin D23-reduktaza (EC 1.3.1.5, NAD(P)H: kukurbitacin B Delta23-oksidoreduktaza) je enzim sa sistematskim imenom 23,24-dihidrokukurbitacin:NAD(P)+ Delta23-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 23,24-dihidrokukurbitacin B + NAD(P)+ kukurbitacin B + NAD(P)H + H+
Za rad ovog enzima je neophodan Mn2+. Fe2+ ili Zn2+ mogu da zemen Mn2+ u izvesnoj meri.
Reference[uredi | uredi kod]
- ↑ Schabort, J.C. and Potgieter, D.J.J. (1968). „Cucurbitacin B Δ23-reductase from Cucurbita maxima. II. Cofactor requirements, enzyme kinetics, substrate specificity and other characteristics”. Biochim. Biophys. Acta 151: 47-53. PMID 4384331.
- ↑ Schabort, J.C., Potgieter, D.J.J. and de Villiers, V. (1968). „Cucurbitacin B Δ23-reductase from Cucurbita maxima. I. Assay methods, isolation and purification”. Biochim. Biophys. Acta 151: 33-46. PMID 5640163.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.