NAD(P)+ transhidrogenaza (AB-specifična)
| NAD(P)+ transhidrogenaza (AB-specifična) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| NAD(P)+ transhidrogenaza heterotrimer, Rhodospirillum rubrum | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.6.1.2 | ||||||||
| CAS broj | 9014-18-0,9072-60-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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NAD(P)+ transhidrogenaza (AB-specifična) (EC 1.6.1.2, piridin nukleotidna transhidrogenaza, transhidrogenaza, NAD(P)+ transhidrogenaza, nikotinamid adenin dinukleotid (fosfat) transhidrogenaza, NAD+ transhidrogenaza, NADH transhidrogenaza, nikotinamid nukleotidna transhidrogenaza, NADPH-NAD+ transhidrogenaza, piridin nukleotidna transferaza, NADPH-NAD+ oksidoreduktaza, NADH-NADP+-transhidrogenaza, NADPH:NAD+ transhidrogenaza, NAD(P)+ transhidrogenaza (AB-specifična)) je enzim sa sistematskim imenom NADPH:NAD+ oksidoreduktaza (AB-specifična).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- NADPH + NAD+ NADP+ + NADH
Ovaj enzim iz srčanih mitohondrija je A-specifičan u pogledu NAD+ i B-specifičan za NADP+.
- ↑ Fisher, R.R. and Earle, S.R. (1982). „Membrane-bound pyridine dinucleotide transhydrogenases”. u: Everse, J., Anderson, B. and You, K.. The Pyridine Nucleotide Coenzymes. New York: The Pyridine Nucleotide Coenzymes. str. 279-324.
- ↑ You, K.-S. (1985). „Stereospecificity for nicotinamide nucleotides in enzymatic and chemical hydride transfer reactions”. CRC Crit. Rev. Biochem. 17: 313-451. PMID 3157549.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.