Glutamat dehidrogenaza
(Preusmjereno sa stranice NAD+-linked glutamate dehydrogenase)
| Glutamat dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.1.2 | ||||||||
| CAS broj | 9001-46-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Glutamat dehidrogenaza (EC 1.4.1.2, glutaminska dehidrogenaza, glutamatna dehidrogenaza (NAD+), glutamatna oksidoreduktaza, glutamatna kiselina dehidrogenaza, L-glutamatna dehidrogenaza, NAD+-zavisna glutamatna dehidrogenaza, NAD+-glutamatna dehidrogenaza, NAD+-vezana glutamatna dehidrogenaza, NAD+-vezana glutamatna dehidrogenaza, NAD+-specifična glutamatna dehidrogenaza, NAD+-specifična glutamatna dehidrogenaza, NAD+:glutamatna oksidoreduktaza, NADH-vezana glutamatna dehidrogenaza) je enzim sa sistematskim imenom L-glutamat:NAD+ oksidoreduktaza (deaminacija).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-glutamat +H2O + NAD+ 2-oksoglutarat + NH3 + NADH + H+
Reference[uredi | uredi kod]
- ↑ Frieden, C. (1963). „L-Glutamate dehydrogenase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 3-24.
- ↑ Nisman, B. (1954). „The Stickland reaction”. Bacteriol. Rev. 18: 16-42. PMID 13140081.
- ↑ Pahlich, E. and Joy, K.W. (1971). „Glutamate dehydrogenase from pea roots: purification and properties of the enzyme”. Can. J. Biochem. 49: 127-138. PMID 4324282.
- ↑ Smith, E.L., Austen, B.M., Blumenthal, K.M. and Nyc, J.F. (1975). „Glutamate dehydrogenases”. u: Boyer, P.D.. The Enzymes. 11 (3rd izd.). New York: Academic Press. str. 293-367.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.