Alanin dehidrogenaza
(Preusmjereno sa stranice NAD+-dependent alanine dehydrogenase)
| Alanin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.1.1 | ||||||||
| CAS broj | 2603971 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Alanin dehidrogenaza (EC 1.4.1.1, AlaDH, L-alaninska dehidrogenaza, NAD+-vezana alaninska dehidrogenaza, alfa-alaninska dehidrogenaza, NAD+-zavisna alaninska dehidrogenaza, alaninska oksidoreduktaza, NADH-zavisna alaninska dehidrogenaza) je enzim sa sistematskim imenom L-alanin:NAD+ oksidoreduktaza (deaminacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-alanin +H2O + NAD+ piruvat + NH3 + NADH + H+
Reference[uredi | uredi kod]
- ↑ O'Connor, R.J. and Halvorson, H. (1961). „The substrate specificity of L-alanine dehydrogenase”. Biochim. Biophys. Acta 48: 47-55. PMID 13730044.
- ↑ Piérard, A. and Wiame, J.M. (1960). „Propriétés de la L(+)-alanine-déshydrogénase”. Biochim. Biophys. Acta 37: 490-502. PMID 14432812.
- ↑ Yoshida, A. and Freese, E. (1965). „Enzymic properties of alanine dehydrogenase of Bacillus subtilis”. Biochim. Biophys. Acta 96: 248-262. PMID 14298830.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.