N-acetilgalaktozamin kinaza
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| N-acetilgalaktozamin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.157 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
N-acetilgalaktozamin kinaza (EC 2.7.1.157, GALK2, GK2, GalNAc kinaza, N-acetilgalaktozamin (GalNAc)-1-fosfat kinaza) je enzim sa sistematskim imenom ATP:N-acetil-D-galaktozamin 1-fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim je visoko specifičan za GalNAc kao supstrat. On u manjoj meri deluje na D-galaktozu.
Reference[uredi | uredi kod]
- ↑ Pastuszak, I., Drake, R. and Elbein, A.D. (1999). „Kidney N-acetylgalactosamine (GalNAc)-1-phosphate kinase, a new pathway of GalNAc activation”. J. Biol. Chem. 271: 20776-20782. PMID 8702831.
- ↑ Pastuszak, I., O'Donnell, J. and Elbein, A.D. (1996). „Identification of the GalNAc kinase amino acid sequence”. J. Biol. Chem. 271: 23653-23656. PMID 8798585.
- ↑ Thoden, J.B. and Holden, H.M. (2005). „The molecular architecture of human N-acetylgalactosamine kinase”. J. Biol. Chem. 280: 32784-32791. PMID 16006554.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.