N-acetilgalaktozamin-N,N'-diacetilbacillosaminil-difosfo-undekaprenol 4-alfa-N-acetilgalaktozaminiltransferaza
| N-acetilgalaktozamin-N,N'-diacetilbacillosaminil-difosfo-undekaprenol 4-alfa-N-acetilgalaktozaminiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.291 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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N-acetilgalaktozamin-N,N'-diacetilbacillosaminil-difosfo-undekaprenol 4-alfa-N-acetilgalaktozaminiltransferaza (EC 2.4.1.291, PglJ) je enzim sa sistematskim imenom UDP-N-acetil-alfa-D-galaktozamin:N-acetilgalaktozaminil-alfa-(1->3)-N,N'-diacetil-alfa-D-bacilozaminil-difosfo-tritrans,heptacis-undekaprenol 3-alfa-N-acetil-D-galaktozaminiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-N-acetil-alfa-D-galaktozamin + N-acetil-D-galaktozaminil-alfa-(1->3)-N,N'-diacetil-alfa-D-bacillosaminil-difosfo-tritrans,heptacis-undekaprenol UDP + N-acetil-D-galaktozaminil-alfa-(1->4)-N-acetil-D-galaktozaminil-alfa-(1->3)-N,N'-diacetil-alfa-D-bacillosaminil-difosfo-tritrans,heptacis-undekaprenol
Ovaj enzim je izolovan iz Campylobacter jejuni.
- ↑ Glover, K.J., Weerapana, E. and Imperiali, B. (2005). „In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation”. Proc. Natl. Acad. Sci. USA 102: 14255-14259. PMID 16186480.
- ↑ Chen, M.M., Weerapana, E., Ciepichal, E., Stupak, J., Reid, C.W., Swiezewska, E. and Imperiali, B. (2007). „Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway”. Biochemistry 46: 14342-14348. PMID 18034500.
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