N-acetilgalaktozaminska 4-sulfataza
(Preusmjereno sa stranice N-acetilgalaktozamin-4-sulfataza)
| N-acetilgalaktozaminska 4-sulfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.6.12 | ||||||||
| CAS broj | 55354-43-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
N-acetilgalaktozaminska 4-sulfataza (EC 3.1.6.12, hondroitinsulfataza, hondroitinaza, arilsulfataza B, acetilgalaktozamin 4-sulfataza, N-acetilgalaktozamin 4-sulfat sulfohidrolaza) je enzim sa sistematskim imenom N-acetil-D-galaktozamin-4-sulfat 4-sulfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza 4-sulfatnih grupa N-acetil-D-galaktozamin 4-sulfatnih jedinica hondroitin sulfata i dermatan sulfata
Ovaj enzim takođe deluje na N-acetilglukozamin 4-sulfat.
Reference[uredi | uredi kod]
- ↑ Farooqui, A.A. (1976). „The desulphation of hexosamine sulphates by arylsulphatase B”. Experientia 32: 1242-1244. PMID 976430.
- ↑ Gorham, S.D. and Cantz, M. (1978). „Arylsulphatase B, an exo-sulphatase for chondroitin 4-sulphate tetrasaccharide”. Hoppe-Seyler's Z. Physiol. Chem. 359: 1811-1814. PMID 738706.
- ↑ Tsuji, M., Nakanishi, Y., Habuchi, H., Ishihara, K. and Suzuki, S. (1980). „The common identity of UDP-N-acetylgalactosamine 4-sulfatase, nitrocatechol sulfatase (arylsulfatase), and chondroitin 4-sulfatase”. Biochim. Biophys. Acta 612: 373-383. PMID 7370276.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.