N-acetilglukozaminildifosfodolihol N-acetilglukozaminiltransferaza
(Preusmjereno sa stranice N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase)
| N-acetilglukozaminildifosfodolihol N-acetilglukozaminiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.141 | ||||||||
| CAS broj | 75536-54-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
N-acetilglukozaminildifosfodolihol N-acetilglukozaminiltransferaza (EC 2.4.1.141, UDP-GlcNAc:dolihil-pirofosforil-GlcNAc GlcNAc transferaza, uridin difosfoacetilglukozamin-dolihilacetilglukozamin pirofosfat acetilglukozaminiltransferaza, N,N'-diacetilhitobiozilpirofosforildolihol sintaza) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:N-acetil-D-glukozaminil-difosfodolihol N-acetil-D-glukozaminiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-N-acetil-D-glukozamin + N-acetil-D-glukozaminil-difosfodolihol UDP + N,N'-diacetilhitobiozil-difosfodolihol
Reference[uredi | uredi kod]
- ↑ Sharma, C.B., Lehle, L. and Tanner, W. (1982). „Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast”. Eur. J. Biochem. 126: 319-325. PMID 6215245.
- ↑ Turco, S.J. and Heath, E.C. (1977). „Glucuronosyl-N-acetylglucosaminyl pyrophosphoryldolichol. Formation in SV40-transformed human lung fibroblasts and biosynthesis in rat lung microsomal preparations”. J. Biol. Chem. 252: 2918-2928. PMID 192724.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.