Limonen-1,2-diol dehidrogenaza
| Limonen-1,2-diol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.297 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Limonen-1,2-diol dehidrogenaza (EC 1.1.1.297, NAD+-zavisna limonen-1,2-diolna dehidrogenaza) je enzim sa sistematskim imenom ment-8-en-1,2-diol:NAD+ oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ment-8-en-1,2-diol + NAD+ 1-hidroksiment-8-en-2-on + NADH + H+ (generalna reakcija)
- (1) (1S,2S,4R)-ment-8-en-1,2-diol + NAD+ (1S,4R)-1-hidroksiment-8-en-2-on + NADH + H+
- (2) (1R,2R,4S)-ment-8-en-1,2-diol + NAD+ (1R,4S)-1-hidroksiment-8-en-2-on + NADH + H+
Enzim iz gram-pozitivne bakterije Rhodococcus eritropolis DCL14 može da koristi (1S,2S,4R)- i (1R,2R,4S)-ment-8-en-1,2-diol kao supstrat. Aktivnost je viša sa (1S,2S,4R)-ment-8-en-1,2-diolom kao supstratom.
- ↑ van der Werf, M.J., Swarts, H.J. and de Bont, J.A. (1999). „Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene”. Appl. Environ. Microbiol. 65: 2092-2102. PMID 10224006.
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