Karotenoidna 1,2-hidrataza
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| Karotenoidna 1,2-hidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.131 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Karotenoidna 1,2-hidrataza (EC 4.2.1.131, CrtC) je enzim sa sistematskim imenom likopen hidrolijaza (formira 1-hidroksi-1,2-dihidrolikopen).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1) 1-hidroksi-1,2-dihidrolikopen likopen + H2O;;
- (2) 1,1'-dihidroksi-1,1',2,2'-tetrahidrolikopen 1-hidroksi-1,2-dihidrolikopen + H2O
U Rubrivivax gelatinosus i Tiocapsa roseopersicina se formiraju oba produkta.
Reference[uredi | uredi kod]
- ↑ Steiger, S., Mazet, A. and Sandmann, G. (2003). „Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus”. Arch. Biochem. Biophys. 414: 51-58. PMID 12745254.
- ↑ Hiseni, A., Arends, I.W. and Otten, L.G. (2011). „Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina”. Appl. Microbiol. Biotechnol.: -. PMID 21590288.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.