Karbazol 1,9a-dioksigenaza
| Karbazol 1,9a-dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.12.22 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Karbazol 1,9a-dioksigenaza (EC 1.14.12.22, CARDO) je enzim sa sistematskim imenom 9H-karbazol,NAD(P)H:kiseonik oksidoreduktaza (2,3-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 9H-karbazol + NAD(P)H + H+ + O2 2'-aminobifenil-2,3-diol + NAD(P)+
Ovaj enzim katalizuje prvu reakciju degradacije karbazola.
- ↑ Nam, J.W., Nojiri, H., Noguchi, H., Uchimura, H., Yoshida, T., Habe, H., Yamane, H. and Omori, T. (2002). „Purification and characterization of carbazole 1,9a-dioxygenase, a three-component dioxygenase system of Pseudomonas resinovorans strain CA10”. Appl. Environ. Microbiol. 68: 5882-5890. PMID 12450807.
- ↑ Gai, Z., Wang, X., Liu, X., Tai, C., Tang, H., He, X., Wu, G., Deng, Z. and Xu, P. (2010). „The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5”. PLoS One 5: #e10018-e10018. PMID 20368802.
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