IgA-specifična metaloendopeptidaza
(Preusmjereno sa stranice IgA-specific metalloendopeptidase)
| IgA-specifična metaloendopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.13 | ||||||||
| CAS broj | 72231-73-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
IgA-specifična metaloendopeptidaza (EC 3.4.24.13, proteinaza imunoglobulina A1, IgA proteaza, IgA1-specifična proteinaza, IgA1 proteaza, IgA1 proteinaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje Pro-Thr veze na regionu šarke teškog lanca ljudskog IgA
Ovaj enzim je prisutan u nekoliko patogenih vrsta Streptococcus.
Reference[uredi | uredi kod]
- ↑ Kornfeld, S.J. and Plaut, A.G. (1981). „Secretory immunity and the bacterial IgA proteases”. Rev. Infect. Dis. 3: 521-534. PMID 6792682.
- ↑ Gilbert, J.V., Plaut, A.G. and Wright, A. (1991). „Analysis of the immunoglobulin A protease gene of Streptococcus sanguis”. Infect. Immun. 59: 7-17. PMID 1987065.
- ↑ Gilbert, J.V., Plaut, A.G., Fishman, Y. and Wright, A. (1988). „Cloning of the gene encoding streptococcal immunoglobulin A protease and its expression in Escherichia coli”. Infect. Immun. 56: 1961-1966. PMID 3294181.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.