Laktozilkeramid 4-a-galaktoziltransferaza
(Preusmjereno sa stranice Globotriaozilkeramid/CD77 sintaza)
| Laktozilkeramid 4-a-galaktoziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.228 | ||||||||
| CAS broj | 52725-57-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Laktozilkeramid 4-a-galaktoziltransferaza (EC 2.4.1.228, Galbeta1-4Glcbeta1-Cer alfa1,4-galaktoziltransferaza, globotriaozilkeramid/CD77 sintaza, histo-krvna grupa Pk UDP-galaktoza, UDP-galaktoza:laktozilkeramid 4II-alfa-D-galaktoziltransferaza, UDP-galaktoza:beta-D-galaktozil-(1->4)-D-glukozil(1<->1)keramid 4II-alfa-D-galaktoziltransferaza, UDP-galaktoza:beta-D-galaktozil-(1->4)-D-glukozil-(1<->1)-keramid 4II-alfa-D-galaktoziltransferaza) je enzim sa sistematskim imenom UDP-alfa-D-galaktoza:beta-D-galaktozil-(1->4)-D-glukozil-(1<->1)-keramid 4II-alfa-D-galaktoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-alfa-D-galaktoza + beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid UDP + alfa-D-galaktozil-(1->4)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid
Reference[uredi | uredi kod]
- ↑ Bailly, P., Piller, F., Cartron, J.P., Leroy, Y. and Fournet, B. (1986). „Identification of UDP-galactose: lactose (lactosylceramide) α-4 and β-3 galactosyltransferases in human kidney”. Biochem. Biophys. Res. Commun. 141: 84-91. PMID 3099784.
- ↑ Steffensen, R., Carlier, K., Wiels, J., Levery, S.B., Stroud, M., Cedergren, B., Nilsson Sojka, B., Bennett, E.P., Jersild, C. and Clausen, H. (2000). „Cloning and expression of the histo-blood group Pk UDP-galactose: Galβ1-4Glcβ1-Cer α1,4-galactosyltransferase. Molecular genetic basis of the p phenotype”. J. Biol. Chem. 275: 16723-16729. PMID 10747952.
- ↑ Kojima, Y., Fukumoto, S., Furukawa, K., Okajima, T., Wiels, J., Yokoyama, K., Suzuki, Y., Urano, T., Ohta, M. and Furukawa, K. (2000). „Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids”. J. Biol. Chem. 275: 15152-15156. PMID 10748143.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.