Nodavirusna endopeptidaza
(Preusmjereno sa stranice Flock House virus endopeptidase)
Nodavirusna endopeptidaza | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 3.4.23.44 | ||||||||
CAS broj | 852954-38-2 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
Nodavirusna endopeptidaza (EC 3.4.23.44, virusna endopeptidaza crne bube, stajna virusna endopeptidaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza asparaginilne veze tokom maturacije strukturnih proteina virusa, tipično -Asn-Ala- ili -Asn-Phe-
Ovaj enzim kodira nekoliko nodavirusa koji su patogeni za insekte.
Reference[uredi | uredi kod]
- ↑ Zlotnick, A., Reddy, V.S., Dasgupta, R., Schneemann, A. (1994). „, Ray,W.J., Jr., Rueckert, R.R. and Johnson, J.E. Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue”. J. Biol. Chem. 269: 13680-13684. PMID 8175803.
- ↑ Johnson, J.E. and Schneemann, A. (1998). „Nodavirus endopeptidase”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 964-967.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Johnson, J.E. and Schneemann, A. (1998). „Nodavirus endopeptidase”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 964-967.