Dipeptidilna peptidaza III
(Preusmjereno sa stranice Enkephalinase B)
| Dipeptidilna peptidaza III | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.14.4 | ||||||||
| CAS broj | 77464-87-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Dipeptidilna peptidaza III (EC 3.4.14.4, dipeptidil aminopeptidaza III, dipeptidil arilamidaza III, enkefalinaza B, angiotenzinaza crvenih ćelija) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvajanje N-terminalnog dipeptida sa peptida koji sadrži četiri ili više ostataka, sa širokom specifičnošću. Takođe deluje na dipeptidil 2-naftilamide.
Ova citozolna peptidaza je aktivna pri neutralnom pH.
Reference[uredi | uredi kod]
- ↑ McDonald, J.K. (1998). „Dipeptidyl-peptidase III”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 536-538.
- ↑ Fukasawa, K., Fukasawa, K.M., Iwamoto, H., Hirose, J. and Harada, M. (1999). „The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme”. Biochemistry 38: 8299-8303. PMID 10387075.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- McDonald, J.K. (1998). „Dipeptidyl-peptidase III”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 536-538.