Ekso-1,4-beta-D-glukozaminidaza
Izgled
Ekso-1,4-beta-D-glukozaminidaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.2.1.165 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ekso-1,4-beta-D-glukozaminidaza (EC 3.2.1.165, CsxA, GlcNaza, eksohitozanaza, GlmA, ekso-beta-D-glukozaminidaza, hitozan ekso-1,4-beta-D-glukozaminidaza) je enzim sa sistematskim imenom hitozan ekso-(1->4)-beta-D-glukosaminidaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza hitozana ili hitozan oligosaharida čime se sukcesivno odvajaju D-glukozaminski ostataci sa neredukujućeg kraja
Hitozan je parcijalno ili totalno N-deacetilisan hitinski derivat koji je prisutan u ćelijskim zidovima pojedinih fitopatogenih gljiva.
- ↑ Nanjo, F., Katsumi, R. and Sakai, K. (1990). „Purification and characterization of an exo-β-D-glucosaminidase, a novel type of enzyme, from Nocardia orientalis”. J. Biol. Chem. 265: 10088-10094. PMID 2351651.
- ↑ Nogawa, M., Takahashi, H., Kashiwagi, A., Ohshima, K., Okada, H. and Morikawa, Y. (1998). „Purification and characterization of exo-β-D-glucosaminidase from a cellulolytic fungus, Trichoderma reesei PC-3-7”. Appl. Environ. Microbiol. 64: 890-895. PMID 16349528.
- ↑ Fukamizo, T., Fleury, A., Côté, N., Mitsutomi, M. and Brzezinski, R. (2006). „Exo-β-D-glucosaminidase from Amycolatopsis orientalis: catalytic residues, sugar recognition specificity, kinetics, and synergism”. Glycobiology 16: 1064-1072. PMID 16877749.
- ↑ Côté, N., Fleury, A., Dumont-Blanchette, E., Fukamizo, T., Mitsutomi, M. and Brzezinski, R. (2006). „Two exo-β-D-glucosaminidases/exochitosanases from actinomycetes define a new subfamily within family 2 of glycoside hydrolases”. Biochem. J. 394: 675-686. PMID 16316314.
- ↑ Ike, M., Isami, K., Tanabe, Y., Nogawa, M., Ogasawara, W., Okada, H. and Morikawa, Y. (2006). „Cloning and heterologous expression of the exo-β-D-glucosaminidase-encoding gene (gls93) from a filamentous fungus, Trichoderma reesei PC-3-7”. Appl. Microbiol. Biotechnol. 72: 687-695. PMID 16636831.
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