2-Metilinglutaratna mutaza
(Preusmjereno sa stranice EC 5.4.99.4)
| 2-Metilinglutaratna mutaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.4.99.4 | ||||||||
| CAS broj | 2615048 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
2-Metilinglutaratna mutaza (EC 5.4.99.4, alfa-metilinglutaratna mutaza) je enzim sa sistematskim imenom 2-metilinglutarat karboksi-metilinmetilmutaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2-metilinglutarat 2-metilin-3-metilsukcinat
Za dejstvo ovog enzima je neophodan kobamidni koenzim.
Reference[uredi | uredi kod]
- ↑ Kung, H.-F., Cederbaum, S., Tsai, L. and Stadtman, T.C. (1970). „Nicotinic acid metabolism. V. A cobamide coenzyme-dependent conversion of α-methyleneglutaric acid to dimethylmaleic acid”. Proc. Natl. Acad. Sci. USA 65: 978-984. PMID 5266166.
- ↑ Kung, H.-F. and Stadtman, T.C. (1971). „Nicotinic acid metabolism. VI. Purification and properties of α-methyleneglutarate mutase (B12-dependent) and methylitaconate isomerase”. J. Biol. Chem. 246: 3378-3388. PMID 5574401.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.