N-acetilglukozaminska 6-sulfataza
(Preusmjereno sa stranice EC 3.1.6.14)
| N-acetilglukozaminska 6-sulfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.6.14 | ||||||||
| CAS broj | 65666-34-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
N-acetilglukozaminska 6-sulfataza (EC 3.1.6.14, hondroitinsulfataza, O,N-disulfat O-sulfohidrolaza, acetilglukozamin 6-sulfataza, N-acetilglukozamin 6-sulfat sulfataza, acetilglukozamin 6-sulfataza, 2-acetamido-2-dezoksi-D-glukoza 6-sulfat sulfataza) je enzim sa sistematskim imenom N-acetil-D-glukozamin-6-sulfat 6-sulfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza 6-sulfatnih grupa N-acetil-D-glukozamin 6-sulfatnih jedinica heparan sulfata i keratan sulfata
Ovaj enzim može da bude identičan enzimom EC 3.1.6.11, disulfoglukozamin-6-sulfatazom.
Reference[uredi | uredi kod]
- ↑ Basner, R., Kresse, H. and von Figura, K. (1979). „N-Acetylglucosamine-6-sulfate sulfatase from human urine”. J. Biol. Chem. 254: 1151-1158. PMID 762121.
- ↑ Kresse, H., Fuchs, W., Glössl, J., Holtfrerich, D. and Gilberg, W. (1981). „Liberation of N-acetylglucosamine-6-sulfate by human β-N-acetylhexosaminidase A”. J. Biol. Chem. 256: 12926-12932. PMID 6458607.
- ↑ Weissmann, B., Chao, H. and Chow, P. (1980). „A glucosamine O,N-disulfate O-sulfohydrolase with a probable role in mammalian catabolism of heparan sulfate”. Biochem. Biophys. Res. Commun. 97: 827-833. PMID 6451222.
Literatura[uredi | uredi kod]
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- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.