Tetrahidroberberin oksidaza
(Preusmjereno sa stranice EC 1.3.3.8)
| Tetrahidroberberin oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.3.8 | ||||||||
| CAS broj | 114705-00-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Tetrahidroberberin oksidaza (EC 1.3.3.8, (S)-THB oksidaza) je enzim sa sistematskim imenom (S)-tetrahidroberberin:kiseonik oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (S)-tetrahidroberberin + 2 O2 berberin + 2H2O2
Enzim iz Berberis sp. je flavoprotein, dok enzim iz Coptis japonica nije. (R)-tetrahidroberberini nisu supstrat ovog enzima.
Reference[uredi | uredi kod]
- ↑ Amann, M., Nagakura, N. and Zenk, M.H. (1984). „(S)-Tetrahydroprotoberberine oxidase the final enzyme in protoberberine biosynthesis”. Tetrahedron Lett. 25: 953-954.
- ↑ Okada, N., Shinmyo, A., Okada, H. and Yamada, Y. (1988). „Purification and characterization of (S)-tetrahydroberberine oxidase from cultured Coptis japonica cells”. Phytochemistry 27: 979-982.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.