3b-hidroksi-5b-steroid dehidrogenaza
(Preusmjereno sa stranice EC 1.1.1.277)
| 3b-hidroksi-5b-steroid dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.277 | ||||||||
| CAS broj | 162731-81-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
3b-hidroksi-5b-steroid dehidrogenaza (EC 1.1.1.277, 3beta-hidroksisteroid 5beta-oksidoreduktaza, 3beta-hidroksisteroid 5beta-progesteron oksidoreduktaza) je enzim sa sistematskim imenom 3beta-hidroksi-5beta-steroid:NADP+ 3-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3beta-hidroksi-5beta-pregnan-20-on + NADP+ 5beta-pregnan-3,20-dion + NADPH + H+
Reference[uredi | uredi kod]
- ↑ Stuhlemmer, U. and Kreis, W. (1996). „Cardenolide formation and activity of pregnane-modifying enzymes in cell suspension cultures, shoot cultures and leaves of Digitalis lanata”. Plant Physiol. 34: 85-91.
- ↑ Seitz, H.U. and Gaertner, D.E. (1994). „Enzymes in cardenolide-accumulating shoot cultures of Digitalis purpurea”. Plant Cell 38: 337-344.
- ↑ Lindemann, P. and Luckner, M. (1997). „Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata”. Phytochemistry 46: 507-513.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.