Sulkaton reduktaza
(Preusmjereno sa stranice EC 1.1.1.260)
| Sulkaton reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.260 | ||||||||
| CAS broj | 196522-54-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Sulkaton reduktaza (EC 1.1.1.260, sulkatonska reduktaza) je enzim sa sistematskim imenom sulkatol:NAD+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- sulkatol + NAD+ sulkaton + NADH + H+
Istraživanja uticaja stadijuma rasta i snabdevanja nutrijentima na stereohemiju sulkatonske redukcije kod Clostridia pasteurianum, C. tyrobutirnaum i Lactobacillus brevis sugeriraju da postoje najmanje dve sulkatonske reduktaze sa različitim stereospecifičnostima.
Reference[uredi | uredi kod]
- ↑ Belan, A., Botle, J., Fauve, A., Gourcy, J.G. and Veschambre, H. (1987). „Use of biological systems for the preparation of chiral molecules. 3. An application in pheromone synthesis: Preparation of sulcatol enantiomers”. J. Org. Chem. 52: 256-260.
- ↑ Tidswell, E.C., Salter, G.J., Kell, D.B. and Morris, J.G. (1997). „Enantioselectivity of sulcatone reduction by some anaerobic bacteria”. Enzyme Microb. Technol. 21: 143-147.
- ↑ Tidswell, E.C., Thompson, A.N. and Morris, J.G. (1991). „Selection in chemostat culture of a mutant strain of Clostridium tryobutyricum improved in its reduction of ketones”. J. Appl. Microbiol. Biotechnol. 35: 317-322.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.