2-alkin-1-ol dehidrogenaza
(Preusmjereno sa stranice EC 1.1.1.165)
| 2-alkin-1-ol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.165 | ||||||||
| CAS broj | 54576-94-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
2-alkin-1-ol dehidrogenaza (EC 1.1.1.165, 2-alkin-1-olna dehidrogenaza) je enzim sa sistematskim imenom 2-butin-1,4-diol:NAD+ 1-oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2-butin-1,4-diol + NAD+ 4-hidroksi-2-butinal + NADH + H+
Ovaj enzim deluje na mnoštvo 2-alkin-1-ola, kao i na 1,4-butandiol. NADP+ takođe deluje kao acceptor, mada sporije.
Reference[uredi | uredi kod]
- ↑ Miyoshi, T., Sato, H. and Harada, T. (1974). „Purification and characterization of 2-alkyne-1-ol dehydrogenase induced by 2-butene-1,4-diol in Fusarium merismoides B11”. Biochim. Biophys. Acta 358: 231-239.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.