DTDP-4-amino-4,6-didezoksi-D-galaktoza aciltransferaza
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| DTDP-4-amino-4,6-didezoksi-D-galaktoza aciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.210 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
DTDP-4-amino-4,6-didezoksi-D-galaktoza aciltransferaza (EC 2.3.1.210, TDP-fukozaminska acetiltransferaza, WecD, RffC) je enzim sa sistematskim imenom acetil-KoA:dTDP-4-amino-4,6-didezoksi-alfa-D-galaktoza N-acetiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + dTDP-4-amino-4,6-didezoksi-alfa-D-galaktoza KoA + dTDP-4-acetamido-4,6-didezoksi-alfa-D-galaktoza
Produkt, TDP-4-acetamido-4,6-didezoksi-D-galaktoza, se koristi u biosintezi enterobakterijskog zajedničkog antigena (ECA).
Reference[uredi | uredi kod]
- ↑ Hung, M.N., Rangarajan, E., Munger, C., Nadeau, G., Sulea, T. and Matte, A. (2006). „Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis”. J. Bacteriol. 188: 5606-5617. PMID 16855251.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.