D24(241)-sterol reduktaza
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| D24(241)-sterol reduktaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 1.3.1.71 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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D24(241)-sterol reduktaza (EC 1.3.1.71, sterol Delta24(28)-metilinska reduktaza, sterolna Delta24(28)-reduktaza) je enzim sa sistematskim imenom ergosterol:NADP+ Delta24(241)-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ergosterol + NADP+ ergosta-5,7,22,24(241)-tetraen-3beta-ol + NADPH + H+
Ovaj enzim deluje opseg steroida sa 24(241)-dvostrukom vezom.
Reference[uredi | uredi kod]
- ↑ Neal, W.D. and Parks, L.W. (1977). „Sterol 24(28) methylene reductase in Saccharomyces cerevisiae”. J. Bacteriol. 129: 1375-1378. PMID 14922.
- ↑ Zweytick, D., Hrastnik, C. (2000). „, Kohlwein. S.D. and Daum, G. Biochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast Saccharomyces cerevisiae”. FEBS Lett. 470: 83-87. PMID 10722850.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.