3-dehidrosfinganin reduktaza
(Preusmjereno sa stranice D-3-oksosfinganin:B-NADPH oksidoreduktaza)
| 3-dehidrosfinganin reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.102 | ||||||||
| CAS broj | 37250-36-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
3-dehidrosfinganin reduktaza (EC 1.1.1.102, D-3-dehidrosfinganinska reduktaza, D-3-oksosfinganinska reduktaza, DSR, 3-oksosfinganinska reduktaza, 3-oksosfinganin:NADPH oksidoreduktaza, D-3-oksosfinganin:B-NADPH oksidoreduktaza) je enzim sa sistematskim imenom D-eritro-dihidrosphingosine:NADP+ 3-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- sfinganin + NADP+ 3-dehidrosfinganin + NADPH + H+
Reference[uredi | uredi kod]
- ↑ Stoffel, W., Le Kim, D. and Sticht, G. (1968). „Biosynthesis of dihydrosphingosine in vitro”. Hoppe-Seyler's Z. Physiol. Chem. 349: 664-670. PMID 4386961.
- ↑ Stoffel, W., Le Kim, D. and Sticht, G. (1968). „Metabolism of sphingosine bases. 8. Distribution, isolation and properties of D-3-oxosphinganine reductase. Stereospecificity of the NADPH-dependent reaction of 3-oxodihydrospingosine (2-amino-1-hydroxyoctadecane-3-one)”. Hoppe-Seyler's Z. Physiol. Chem. 349: 1637-1644. PMID 4387676.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.