CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza

CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza
	CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza homodimer, Mycobacterium tuberculosis
Identifikatori
EC broj	2.7.8.11
CAS broj	2603088
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza (EC 2.7.8.11, CDP-diglicerid-inozitolna fosfatidiltransferaza, fosfatidilinozitolna sintaza, CDP-diacilglicerol-inozitolna fosfatidiltransferaza, CDP-diglicerid:inozitol transferaza, citidin 5'-difosfo-1,2-diacil-sn-glicerol:mio-inozitol 3-fosfatidiltransferaza, CDP-DG:inozitol transferaza, citidin difosfodiglicerid-inozitolna fosfatidiltransferaza, CDP-diacilglicerol:mio-inozitol-3-fosfatidiltransferaza, CDP-diglicerid-inozitolna transferaza, citidin difosfoglicerid-inozitolna fosfatidiltransferaza, citidin difosfoglicerid-inozitolna transferaza) je enzim sa sistematskim imenom CDP-diacilglicerol:mio-inozitol 3-fosfatidiltransferaza.^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

CDP-diacilglicerol + mio-inozitol

\rightleftharpoons

CMP + 1-fosfatidil-1D-mio-inozitol

Reference[uredi | uredi kod]

↑ Bleasdale, J.E., Wallis, P., MacDonald, P.C. and Johnston, J.M. (1979). „Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue”. Biochim. Biophys. Acta 575: 135-147. PMID 41587.
↑ Prottey, C. and Hawthorne, J.N. (1967). „The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas”. Biochem. J. 105: 379-392. PMID 4293959.
↑ Salway, J.G., Harewood, J.L., Kai, M., White, G.L. and Hawthorne, J.N. (1968). „Enzymes of phosphoinositide metabolism during rat brain development”. J. Neurochem. 15: 221-226. PMID 4295616.
↑ Takenawa, T. and Egawa, K. (1977). „CDP-diglyceride:inositol transferase from rat liver. Purification and properties”. J. Biol. Chem. 252: 5419-5423. PMID 18462.

Literatura[uredi | uredi kod]

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze[uredi | uredi kod]

MeSH CDP-diacylglycerol---inositol+3-phosphatidyltransferase

[1] Bleasdale, J.E., Wallis, P., MacDonald, P.C. and Johnston, J.M. (1979). „Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue”. Biochim. Biophys. Acta 575: 135-147. PMID 41587.

[2] Prottey, C. and Hawthorne, J.N. (1967). „The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas”. Biochem. J. 105: 379-392. PMID 4293959.

[3] Salway, J.G., Harewood, J.L., Kai, M., White, G.L. and Hawthorne, J.N. (1968). „Enzymes of phosphoinositide metabolism during rat brain development”. J. Neurochem. 15: 221-226. PMID 4295616.

[4] Takenawa, T. and Egawa, K. (1977). „CDP-diglyceride:inositol transferase from rat liver. Purification and properties”. J. Biol. Chem. 252: 5419-5423. PMID 18462.

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[2]

[3]

[4]

p r u Proteini: enzimi
Teme	Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
Tipovi	EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6

CDP-diacilglicerol—inozitol 3-fosfatidiltransferaza

Reference[uredi | uredi kod]

Literatura[uredi | uredi kod]

Vanjske veze[uredi | uredi kod]

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