Delta8-masna-kiselina desaturaza
(Preusmjereno sa stranice BoDES8)
| Delta8-masna-kiselina desaturaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.19.4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Delta8-masna-kiselina desaturaza (EC 1.14.19.4, Delta8-sfingolipidna desaturaza, EFD1, BoDES8, SLD, Delta8 masno kiselinska desaturaza, Delta8-desaturaza) je enzim sa sistematskim imenom fitosfinganin,vodonik donor:kiseonik Delta8-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- fitosfinganin + redukovani akceptor + O2 Delta8-fitosfingenin + akceptor + 2H2O
Ovaj enzim je prisutan u mnogim biljkama. On uvodi dvostruku vezu u Delta8 kod C18 i C20 masnih kiselina.
- ↑ Wallis, J.G. and Browse, J. (1999). „The Δ8-desaturase of Euglena gracilis: an alternate pathway for synthesis of 20-carbon polyunsaturated fatty acids”. Arch. Biochem. Biophys. 365: 307-316. PMID 10328826.
- ↑ Sperling, P., Libisch, B., Zähringer, U., Napier, J.A. and Heinz, E. (2001). „Functional identification of a Δ8-sphingolipid desaturase from Borago officinalis”. Arch. Biochem. Biophys. 388: 293-298. PMID 11368168.
- ↑ Takakuwa, N., Kinoshita, M., Oda, Y. and Ohnishi, M. (2002). „Isolation and characterization of the genes encoding Δ8-sphingolipid desaturase from Saccharomyces kluyveri and Kluyveromyces lactis'”. Curr. Microbiol. 45: 459-461. PMID 12402089.
- ↑ Beckmann, C., Rattke, J., Oldham, N.J., Sperling, P., Heinz, E. and Boland, W. (2002). „Characterization of a Δ8-sphingolipid desaturase from higher plants: a stereochemical and mechanistic study on the origin of E,Z isomers”. Angew. Chem. Int. Ed. Engl. 41: 2298-2300. PMID 12203571.
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