Aralkilamin dehidrogenaza (azurin)
| Aralkilamin dehidrogenaza (azurin) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.9.2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Aralkilamin dehidrogenaza (azurin) (EC 1.4.9.2, aromatična aminska dehidrogenaza, arilaminska dehidrogenaza, tiraminska dehidrogenaza, aralkilamin:(akceptor) oksidoreduktaza (deaminacija)) je enzim sa sistematskim imenom aralkilamin:azurin oksidoreduktaza (deaminacija).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ArCH2NH2 + H2O + 2 azurin ArCHO + NH3 + 2 redukovani azurin
Fenazinski metosulfat može da deluje kao akceptor. Ovaj enzim deluje na aromatične amine i u manjoj meri na pojedine dugolančane alifatične amine.
- ↑ Iwaki, M., Yagi, T., Horiike, K., Saeki, Y., Ushijima, T. and Nozaki, M. (1983). „Crystallization and properties of aromatic amine dehydrogenase from Pseudomonas sp”. Arch. Biochem. Biophys. 220: 253-262. PMID 6830237.
- ↑ Hyun, Y.L. and Davidson, V.L. (1995). „Electron transfer reactions between aromatic amine dehydrogenase and azurin”. Biochemistry 34: 12249-12254. PMID 7547967.
- ↑ Hyun, Y.L., Zhu, Z. and Davidson, V.L. (1999). „Gated and ungated electron transfer reactions from aromatic amine dehydrogenase to azurin”. J. Biol. Chem. 274: 29081-29086. PMID 10506161.
- ↑ Davidson, V.L. (2004). „Electron transfer in quinoproteins”. Arch. Biochem. Biophys. 428: 32-40. PMID 15234267.
- ↑ Sukumar, N., Chen, Z.W., Ferrari, D., Merli, A., Rossi, G.L., Bellamy, H.D., Chistoserdov, A., Davidson, V.L. and Mathews, F.S. (2006). „Crystal structure of an electron transfer complex between aromatic amine dehydrogenase and azurin from Alcaligenes faecalis”. Biochemistry 45: 13500-13510. PMID 17087503.
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