Alifatična aldoksimna dehidrataza
Prijeđi na navigaciju
Prijeđi na pretragu
| Alifatična aldoksimna dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.99.1.5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Alifatična aldoksimna dehidrataza (EC 4.99.1.5, OxdA, alifatična aldoksimska hidrolijaza) je enzim sa sistematskim imenom alifatični aldoksim hidrolijaza (formira alifatični-nitril).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- alifatični aldoksim alifatični nitril + H2O
Enzim iz Pseudomonas hlororaphis sadrži Ca2+ i protohem IX.
Reference[uredi | uredi kod]
- ↑ Oinuma, K.-I., Hashimoto, Y., Konishi, K., Goda, M., Noguchi, T., Higashibata, H. and Kobayashi, M. (2003). „Novel aldoxime dehydratase involved in carbon-nitrogen triple bond synthesis of Pseudomonas chlororaphis B23: Sequencing, gene expression, purification and characterization”. J. Biol. Chem. 278: 29600-29608. PMID 12773527.
- ↑ Xie, S.X., Kato, Y., Komeda, H., Yoshida, S. and Asano, Y. (2003). „A gene cluster responsible for alkylaldoxime metabolism coexisting with nitrile hydratase and amidase in Rhodococcus globerulus A-4”. Biochemistry 42: 12056-12066. PMID 14556637.
- ↑ Kato, Y., Yoshida, S., Xie, S.-X. and Asano, Y. (2004). „Aldoxime dehydratase co-existing with nitrile hydratase and amidase in the iron-type nitrile hydratase-producer Rhodococcus sp. N-771”. J. Biosci. Bioeng. 97: 250-259. PMID 16233624.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.