3,4-Dehidroadipil-KoA semialdehid dehidrogenaza (NADP+)
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| 3,4-Dehidroadipil-KoA semialdehid dehidrogenaza (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.2.1.77 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
3,4-Dehidroadipil-KoA semialdehid dehidrogenaza (NADP+) (EC 1.2.1.77, BoxD, 3,4-dehidroadipil-KoA semialdehid dehidrogenaza) je enzim sa sistematskim imenom 3,4-didehidroadipil-KoA semialdehid:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3,4-didehidroadipil-KoA semialdehid + NADP+ +H2O 3,4-didehidroadipil-KoA + NADPH + H+
Ovaj enzim katalizuje jedan korak u aerobnom benzoil-koenzim A kataboličkom putu kod Azoarcus evansii i Burkholderia xenovorans.
Reference[uredi | uredi kod]
- ↑ Gescher, J., Ismail, W., Olgeschlager, E., Eisenreich, W., Worth, J. and Fuchs, G. (2006). „Aerobic benzoyl-coenzyme A (CoA) catabolic pathway in Azoarcus evansii: conversion of ring cleavage product by 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase”. J. Bacteriol. 188: 2919-2927. PMID 16585753.
- ↑ Bains, J. and Boulanger, M.J. (2008). „Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400”. J. Mol. Biol. 379: 597-608. PMID 18462753.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.