21-hidroksisteroid dehidrogenaza (NAD+)
Prijeđi na navigaciju
Prijeđi na pretragu
21-hidroksisteroid dehidrogenaza (NAD+) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 1.1.1.150 | ||||||||
CAS broj | 37250-75-2 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
21-hidroksisteroid dehidrogenaza (NAD+) (EC 1.1.1.150, 21-hidroksisteroidna dehidrogenaza (NAD+)) je enzim sa sistematskim imenom 21-hidroksisteroid:NAD+ 21-oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- pregnan-21-ol + NAD+ pregnan-21-al + NADH + H+
21-Hidroksisteroidna dehidrogenaza deluje na brojne 21-hidroksikortikosteroide.
- ↑ Monder, C. and White, A. (1965). „The 21-hydroxysteroid dehydrogenases of liver. A nicotinamide adenine dinucleotide phosphate dehydrogenase and two nicotinamide adenine dinucleotide dehydrogenases”. J. Biol. Chem. 240: 71-77. PMID 14253469.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.