16S rRNK pseudouridinska516 sintaza
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| 16S rRNK pseudouridinska516 sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.4.99.19 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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16S rRNK pseudouridinska516 sintaza (EC 5.4.99.19, 16S RNK pseudouridinska516 sintaza, 16S PsiI516 sintaza, 16S RNK Psi516 sintaza, RNK pseudouridinska sintaza RsuA, RsuA, 16S RNK pseudouridin 516 sintaza) je enzim sa sistematskim imenom 16S rRNK-uridin516 uracil mutaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 16S rRNK uridin516 16S rRNK pseudouridin516
Ovaj enzim je specifičan za uridin516 u 16S rRNK.
Reference[uredi | uredi kod]
- ↑ Wrzesinski, J., Bakin, A., Nurse, K., Lane, B.G. and Ofengand, J. (1995). „Purification, cloning, and properties of the 16S RNA pseudouridine 516 synthase from Escherichia coli”. Biochemistry 34: 8904-8913. PMID 7612632.
- ↑ Conrad, J., Niu, L., Rudd, K., Lane, B.G. and Ofengand, J. (1999). „16S ribosomal RNA pseudouridine synthase RsuA of Escherichia coli: deletion, mutation of the conserved Asp102 residue, and sequence comparison among all other pseudouridine synthases”. RNA 5: 751-763. PMID 10376875.
- ↑ Sivaraman, J., Sauve, V., Larocque, R., Stura, E.A., Schrag, J.D., Cygler, M. and Matte, A. (2002). „Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP”. Nat. Struct. Biol. 9: 353-358. PMID 11953756.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.