POLD2

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Polimeraza (DNK vođena), delta 2, pomoćna podjedinica
Dostupne strukture
3E0J
Identifikatori
Simbol POLD2
Vanjski ID OMIM600815 MGI1097163 HomoloGene4538 GeneCards: POLD2 Gene
EC broj 2.7.7.7
Pregled RNK izražavanja
PBB GE POLD2 201115 at tn.png
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 5425 18972
Ensembl ENSG00000106628 ENSMUSG00000020471
UniProt P49005 O35654
Ref. Sekv. (iRNK) NM_001127218 NM_008894
Ref. Sekv. (protein) NP_001120690 NP_032920
Lokacija (UCSC) Chr 7:
44.15 - 44.16 Mb
Chr 11:
5.87 - 5.88 Mb
PubMed pretraga [1] [2]

Delta podjedinica 2 DNK polimeraze je enzim koji je kod ljudi kodiran POLD2 genom.[1][2] Ona je komponenta kompleksa DNK polimeraze delta.

Interakcije[uredi - уреди]

POLD2 formira interakcije sa PCNA.[3]

Reference[uredi - уреди]

  1. Zhang J, Tan CK, McMullen B, Downey KM, So AG (Feb 1996). "Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2)". Genomics 29 (1): 179–86. doi:10.1006/geno.1995.1229. PMID 8530069. 
  2. "Entrez Gene: POLD2 polymerase (DNA directed), delta 2, regulatory subunit 50kDa". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5425. 
  3. Lu, Xiaoqing; Tan Cheng-Keat, Zhou Jin-Qiu, You Min, Carastro L Michael, Downey Kathleen M, So Antero G (Jul 2002). "Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta". J. Biol. Chem. (United States) 277 (27): 24340–5. doi:10.1074/jbc.M200065200. ISSN 0021-9258. PMID 11986310. 

Literatura[uredi - уреди]