UDP-4-amino-4,6-didezoksi-N-acetil-beta-L-altrozamin transaminaza
(Preusmjereno sa stranice UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase)
| UDP-4-amino-4,6-didezoksi-N-acetil-beta-L-altrozamin transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.92 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
UDP-4-amino-4,6-didezoksi-N-acetil-beta-L-altrozamin transaminaza (EC 2.6.1.92, PseC) je enzim sa sistematskim imenom UDP-4-amino-4,6-didezoksi-N-acetil-beta-L-altrosamin:2-oksoglutarat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-4-amino-4,6-didezoksi-N-acetil-beta-L-altrosamin + 2-oksoglutarat UDP-2-acetamido-2,6-didezoksi-beta-L-arabino-heks-4-uloza + L-glutamat
Ovaj enzim je piridoksal-fosfatni protein. Ovaj enzim učestvuje u biosintezi pseudaminske kiselina.
Reference[uredi | uredi kod]
- ↑ Schoenhofen, I.C., McNally, D.J., Vinogradov, E., Whitfield, D., Young, N.M., Dick, S., Wakarchuk, W.W., Brisson, J.R. and Logan, S.M. (2006). „Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways”. J. Biol. Chem. 281: 723-732. PMID 16286454.
- ↑ Schoenhofen, I.C., Lunin, V.V., Julien, J.P., Li, Y., Ajamian, E., Matte, A., Cygler, M., Brisson, J.R., Aubry, A., Logan, S.M., Bhatia, S., Wakarchuk, W.W. and Young, N.M. (2006). „Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori”. J. Biol. Chem. 281: 8907-8916. PMID 16421095.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.