TRNK pseudouridinska38/39 sintaza
(Preusmjereno sa stranice TRNA pseudouridine38/39 synthase)
| TRNK pseudouridinska38/39 sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.4.99.45 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
TRNK pseudouridinska38/39 sintaza (EC 5.4.99.45, Deg1, Pus3p, pseudouridin sintaza 3) je enzim sa sistematskim imenom tRNK-uridin38/39 uracil mutaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- tRNK uridin38/39 tRNK pseudouridin38/39
Enzim iz Saccharomyces cerevisiae je aktivan samo na uridinu38 i uridinu39.
Reference[uredi | uredi kod]
- ↑ Lecointe, F., Simos, G., Sauer, A., Hurt, E.C., Motorin, Y. and Grosjean, H. (1998). „Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of Ψ38 and Ψ39 in tRNA anticodon loop”. J. Biol. Chem. 273: 1316-1323. PMID 9430663.
- ↑ Chen, J. and Patton, J.R. (2000). „Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA”. Biochemistry 39: 12723-12730. PMID 11027153.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.